Current Concepts in Cell Death

Boris Zhivotovsky1, Sten Orrenius1

1 Karolinska Institutet, Stockholm, Sweden
Publication Name:  Current Protocols in Cell Biology
Unit Number:  Unit 18.1
DOI:  10.1002/0471143030.cb1801s11
Online Posting Date:  August, 2001
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This unit attempts to define cell toxicity that leads to cellular demise, with a strong emphasis on cell death via both apoptosis and necrosis, by summarizing some of the more recent developments in cellular, molecular, and biochemical studies of the events that govern the induction and execution of cell death. Specific topics pertaining to cell death include structural changes, macromolecular degradation, cellular signaling, the role of mitochondria, and genetic modulation of apoptotic cell death.

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Table of Contents

  • Cell Death
  • Structural Changes During Cell Death
  • Macromolecular Degradation During Cell Death
  • Cellular Signaling During Cell Death
  • Role of Mitochondria During Cell Death
  • Genetic Modulation of Apoptotic Cell Death
  • Conclusions
  • Literature Cited
  • Tables
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Literature Cited

Literature Cited
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