Risk Assessment in the Research Laboratory

LouAnn C. Burnett1

1 Sandia National Laboratories, Albuquerque, New Mexico
Publication Name:  Current Protocols Essential Laboratory Techniques
Unit Number:  Appendix A.1B
DOI:  10.1002/cpet.16
Online Posting Date:  November, 2017
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Abstract

Risk assessment is a term that is applied to a process that we all use every day to make decisions. Conducting risk assessments while working in the laboratory should be integrated into the research culture. Reagents and equipment used in research laboratories can be hazardous if used improperly or without appropriate precautions. The first step in limiting risk is identifying the materials that can be hazardous. The second step is to assess the risk that they present during the experiments that will take place—a process called risk assessment. Once the hazards are identified and the risks assessed, a risk management strategy can be put in place to reduce the risks to an acceptable level. This process (hazard identification, risk assessment, risk management) must be repeated as often as new materials, new procedures, and new people are introduced into the laboratory. © 2017 by John Wiley & Sons, Inc.

Keywords: risk assessment; hazards; risk; laboratory safety

     
 
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Table of Contents

  • Introduction
  • Procedure
  • Using Risk Assessments to Manage Risk
  • Acknowledgements
  • Resources
  • Figures
  • Tables
     
 
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Materials

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Figures

Videos

Literature Cited

Key References
   Caskey, S., & Sevilla‐Reyes, E. E. (2014). Risk Assessment. In Laboratory Biorisk Management: Biosafety and Biosecurity (R. M. Salerno and J. Gaudioso, eds.), pp. 45–64. CRC Press: Boca Raton, Florida
  Describes the risk assessment process for biorisk management: an integrated approach for biosafety and biosecurity.
   Committee on Prudent Practices for Handling, Storage, and Disposal of Chemicals in Laboratories. (2011). Prudent Practices in the Laboratory: Handling and Disposal of Chemicals, Updated Version. National Academies Press, Washington, D.C.
  This National Research Council document represents a consensus of best practices for handling and disposal of chemicals in laboratories.
   Fleming, D. O. (2006). Risk assessment of biological hazards In Biological Safety: Principles and Practices, 4th edition(D. O. Fleming, & D. L. Hunt, eds) pp. 57–64. ASM Press, Washington, D.C.
  This book is meant to be used as a resource by those who work with biological materials in research, production, or teaching.
   Gribble, L. A., Tria, E. S., & Wallis, L. (2014). The AMP model. In Laboratory Biorisk Management: Biosafety and Biosecurity (R. M. Salerno, & J. Gaudioso, eds.) pp. 31–44. CRC Press: Boca Raton, Florida.
  Describes the risk assessment process for biorisk management: an integrated approach for biosafety and biosecurity.
   Jank, B., Haymerle, H., & Doblhoff‐Dier, O. (1996). Zurich hazard analysis in biotechnology. Nat. Biotechnol. 14, 894–896.
Internet Resources
   http://www.cdc.gov/od/ohs/biosfty/bmbl5/bmbl5toc.htm
  U.S. Department of Health and Human Services. 2007. Biosafety in Microbiological and Biomedical Laboratories, 5th edition.
   http://biosecurity.sandia.gov/ibctr/risk_management/index.html
  Standardized approaches to risk assessment for chemical and biological safety and security.
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