Handling and Restraint

John Donovan1, Patricia Brown2

1 Wyeth Research, Collegeville, Pennsylvania, 2 National Institutes of Health, Bethesda, Maryland
Publication Name:  Current Protocols in Immunology
Unit Number:  Unit 1.3
DOI:  10.1002/0471142735.im0103s73
Online Posting Date:  July, 2006
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Abstract

For the safety of the handler and the animal, proper methods for handling and restraining laboratory animals should be followed. Improper handling can result in increased stress and injury to the animal. In addition, the handler risks injury from bite wounds or scratches inflicted when the animal becomes fearful or anxious. By using sure, direct movements with a determined attitude, the animal can be easily handled and restrained. Animals can be restrained either manually or in a plastic restrainer. The protocols in this unit describe handling and manual restraint of mice, rats, hamsters, and rabbits. Alternate protocols describe restraint using the plastic restrainer.

Keywords: handling; rat; mouse; hamster; rabbit; restrainer; safety

     
 
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Table of Contents

  • Basic Protocol 1: Mouse Handling and Manual Restraint
  • Basic Protocol 2: Rat Handling and Manual Restraint
  • Basic Protocol 3: Hamster Handling and Manual Restraint
  • Alternate Protocol 1: Rodent Restrainers
  • Basic Protocol 4: Rabbit Handling and Manual Restraint
  • Alternate Protocol 2: Rabbit Restrainers
  • Commentary
  • Literature Cited
  • Figures
     
 
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Materials

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Figures

Videos

Literature Cited

Literature Cited
   Fox, J.G., Anderson, L.C., Loew, F.M., and Quimby, F.W. (eds.). 2002. Laboratory Animal Medicine, 2nd ed., pp. 179‐180. Academic Press, San Diego.
   Poole, T.B. (ed.). 1999. The UFAW Handbook on the Care and Management of Laboratory Animals, 7th ed., pp. 325‐326. Blackwell Science Ltd., Oxford.
   Suckow, M.A. and Douglas, F.A. 1997. The Laboratory Rabbit, pp. 71‐74. CRC Press, Boca Raton, Fla.
   Suckow, M.A., Danneman, P., and Brayton, C. 2001. The Laboratory Mouse, p. 113. CRC Press, Boca Raton, Fla.
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