Cytokine, Growth Factor, and Chemokine Ligand Database

Dennis D. Taub1

1 Laboratory of Immunology, Baltimore, MD
Publication Name:  Current Protocols in Immunology
Unit Number:  Unit 6.29
DOI:  10.1002/0471142735.im0629s61
Online Posting Date:  September, 2004
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Abstract

Cytokines, chemokines, and growth factors are soluble proteins produced by leukocytes and other cell types, which act as chemical communicators between cells and tissues within the body. These proteins mediate a number of functions, ranging from effects on cell growth, differentiation, survival, and a number of effector activities. The main purpose of this unit is to provide an easy‐to‐use reference summarizing some of the current information on well‐established cytokine, growth factore, and chemokine ligands. The information provided is confined largely to alternative names, protein properties, genetic chracteristics, chromosomal localization, cellular expression patters, cellular‐tissue targets, stimuli regulating expression, functional properties, expression analysis, and clinical utility.

Keywords: chemokines; cytokines; interleukins; growth factor

     
 
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Table of Contents

  • Acknowledgments
  • Literature Cited
  • Tables
     
 
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Materials

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Figures

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Literature Cited

Literature Cited
   Delves, P.J. and Roitt, I.M. (eds.) 1998. Encyclopedia of Immunology. Academic Press, San Diego.
   Fitzgerald, K.A., O'Neill, L.A.J., Gearing, A.J.H. and Callard, R.E. (eds.) 2001. The Cytokine FactsBook. Academic Press, San Diego.
   Oppenheim, J.J. and Feldman, M. (eds.) 2002. Cytokine Reference. Academic Press, San Diego. [two volumes and online database]
   Paul, W.E. (ed.) 2002. Fundamental Immunology, 4th ed. Lippincott, Williams and Wilkins, San Diego.
   Schaffer, E.S and Taub, D.D. 2001. Cytokine and growth factor and receptor database: Biological, molecular, and pathophysiological properties of ligand‐receptor interactions In Cancer Chemotherapy and Biotherapy, 3rd ed. (B.A. Chabner and D.L. Longo, eds.) pp. 1012‐1015. Lippincott‐Raven Publishers, Philadelphia.
   Thomson, A. (ed.) 1998. The Cytokine Handbook. Acadmeic Press, San Diego, CA.
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