Mouse Endogenous Superantigens: Ms and Mls‐like Determinants Encoded by Mouse Retroviruses

Richard J. Hodes1, Ryo Abe2

1 National Cancer Institute, Bethesda, Maryland, 2 Naval Medical Research Institute, Bethesda, Maryland
Publication Name:  Current Protocols in Immunology
Unit Number:  Appendix 1F
DOI:  10.1002/0471142735.ima01fs17
Online Posting Date:  May, 2001
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Abstract

Commonly used inbred mouse strains express different combinations of integrated mouse mammary tumor proviruses (MMTV). This appendix summarizes the proviruses that have been detected. The reported functional properties of those MMTV proviral products which have been identified as superantigens are also summarized, including the ability to elicit primary or secondary T cell responses and to induce Vbā€specific clonal deletion during T cell differentiation. In addition, the amino acid sequences of putative ORF gene products of different MMTV are compared.

     
 
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Table of Contents

  • Mouse Endogenous Superantigens
  • Literature Cited
  • Tables
     
 
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Materials

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Literature Cited

Literature Cited
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