Commonly Used Rat Strains

Heinz W. Kunz1, Thomas J. Gill1

1 University of Pittsburg School of Medicine, Pittsburg, Pennsylvania
Publication Name:  Current Protocols in Immunology
Unit Number:  Appendix 1H
DOI:  10.1002/0471142735.ima01hs13
Online Posting Date:  May, 2001
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Abstract

It is critical that genetically defined animals be used in immunological studies so that data can be adequately compared both within and between strains to examine the genetic effects on the phenomena being studied. This appendix lists some of the most commonly used rat strains and their immunogenetic properties.

     
 
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Table of Contents

  • Commonly Used Rat Strains
  • Literature Cited
  • Tables
     
 
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Materials

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Literature Cited

Literature Cited
   Cortese Hassett, A.L., Misra, D.N., Kunz, H.W., and Gill, T.J. III. 1991. The major histocompatibility complex of the rat. In Immunogenetics of the Major Histocompatibility Complex (R. Srivastava, B.P. Ram, and P. Tyle, eds.) pp. 309‐347. VCH, New York.
   Gill, T.J. III, Smith, G.J., Wissler, R.W., and Kunz, H.W. 1989. The rat as an experimental animal. Science 245:269‐276.
   Gill, T.J. III., Nomura, T., Festing, M.F.W., Günther, E., Kunz, H.W., Moriwaki, K., and Natori, T. 1992. Definition, nomenclature, and conservation of the rat strains. ILAR News (Institute of Laboratory Animal Resources) 34:S1‐S26.
   Gill, T.J. III., Natori, T., Salgar, S.K., and Kunz, H.W. 1995. Current status of the major histocompatibility complex in the rat. Transplant. Proc. In press.
   Hedrich, H.J., (ed.)1990. Genetic Monitoring of Inbred Strains of Rats. Gustav Fischer Verlag, New York.
   Locker, J., Gill, T.J. III., Kraus, J.P., Ohura, T., Swarop, M., Riviere, M., Islam, M.Q., Levan, G., Szpirer, J., and Szpirer, C. 1990. The rat MHC and cystathionine β‐synthase gene are syntenic on chromosome 20. Immunogenetics 31:271‐274.
   Melhem, M.F., Kunz, H.W., and Gill, T.J. III. 1993. An MHC‐linked locus in the rat critically influences resistance to DEN carcinogenesis. Proc. Natl. Acad. Sci. U.S.A. 90:1967‐1971.
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