Cerebral Infarct/Intracranial Cerebrovascular Disease

P. Ellen Grant1, Pamela W. Schaefer1, R. Gilberto Gonzalez1

1 Massachusetts General Hospital, Boston, Massachusetts
Publication Name:  Current Protocols in Magnetic Resonance Imaging
Unit Number:  Unit A1.1
DOI:  10.1002/0471142719.mia0101s14
Online Posting Date:  December, 2007
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Abstract

Imaging goals for intracranial cerebral vascular disease are (1) to assess the degree of parenchymal injury and identify intraparenchymal hemorrhage; (2) to determine if there are areas of altered perfusion that may be at risk for future injury; and (3) to assess the intracranial arteries (patency as well as direction of flow). This unit describes a Basic Protocol that can be used to evaluate stable patients with acute, subacute, or chronic cerebrovascular symptoms. An Alternate Protocol is also given for cases of hyperacute strokes or cerebrovascular symptoms in an unstable patient.

     
 
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Table of Contents

  • Basic Protocol 1: Standard Imaging for Cerebral Infarct/Intracranial Cerebrovascular Disease
  • Alternate Protocol 1: Rapid Imaging for Acute Cerebral Infarct
  • Commentary
  • Literature Cited
  • Tables
     
 
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Materials

Basic Protocol 1: Standard Imaging for Cerebral Infarct/Intracranial Cerebrovascular Disease

  Materials
  • Normal saline (0.9% NaCl), sterile
  • Gadolinium‐based MR contrast agent (e.g., Magnevist, Omniscan, or Prohance)
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Figures

Videos

Literature Cited

Literature Cited
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   Burdette, J.H., Elster, A.D., and Ricci, P.E. 1999. Acute cerebral infarction: Quantification of spin‐density and T2 shine‐through phenomena on diffusion‐weighted MR images. Radiology 212:333‐339.
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   Sorensen, A.G., Buonanno, F.S., Gonzalez, R.G., Schwamm, L.H., Lev, M.H., Huang‐Hellinger, F.R., Reese, T.G., Weisskoff, R.M., Davis, T.L., Suwanwela, N., Can, U., Moreira, J.A., Copen, W.A., Look, R.B., Finklestein, S.P., Rosen, B.R., and Koroshetz, W.J. 1996. Hyperacute stroke: Evaluation with combined multisection diffusion‐weighted and hemodynamically weighted echo‐planar MR imaging. Radiology 199:391‐401.
   Sorensen, A.G., Copen, W.A., Ostergaard, L., Buonanno, F.S., Gonzalez, R.G., Rordorf, G., Rosen, B.R., Schwamm, L.H., Weisskoff, R.M., and Koroshetz, W.J. 1999. Hyperacute stroke: Simultaneous measurement of relative cerebral blood volume, relative cerebral blood flow, and mean tissue transit time. Radiology 210:519‐527.
   Warach, S., Gaa, J., Siewert, B., Wielopolski, P., and Edelman, R.R. 1995. Acute human stroke studied by whole brain echo planar diffusion‐weighted magnetic resonance imaging. Ann. Neurol. 37:231‐241.
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