Imaging Cavernous Malformations

F. Allan Midyett1, Laurie Fisher2, Suresh Mukherji3

1 UA North Texas Healthcare, Dallas, Texas, 2 Siemens Uptime Service Center, Cary, North Carolina, 3 University of Michigan, Ann Arbor, Michigan
Publication Name:  Current Protocols in Magnetic Resonance Imaging
Unit Number:  Unit A2.2
DOI:  10.1002/0471142719.mia0202s05
Online Posting Date:  August, 2002
GO TO THE FULL TEXT: PDF or HTML at Wiley Online Library

Abstract

This unit describes a for evaluating cavernous malformations (CMs). CMs represent ˜10% to 15% of vascular malformations. They consist of enlarged sinusoidal vascular spaces that have thin walls devoid of smooth muscle and normal endothelium. These form compact masses within central nervous system (CNS) parenchyma or associated structures without normal interspersed tissue. The thin walls lack normal endothelium and are prone to leakage of blood elements.

     
 
GO TO THE FULL PROTOCOL:
PDF or HTML at Wiley Online Library

Table of Contents

  • Basic Protocol 1: Cavernous Malformation
  • Commentary
  • Figures
  • Tables
     
 
GO TO THE FULL PROTOCOL:
PDF or HTML at Wiley Online Library

Materials

Basic Protocol 1: Cavernous Malformation

  Materials
  • Normal saline (0.9% NaCl)
  • Sterile extravascular contrast agent (e.g., Magnevist, Omniscan, Prohance)
GO TO THE FULL PROTOCOL:
PDF or HTML at Wiley Online Library

Figures

Videos

Literature Cited

Literature Cited
   Fischbein, N.J, Dillon, W.P., Barkovich, A.J (eds.) 2000. Teaching Atlas of Brain Imaging, pp. 272‐275. Thieme, New York.
   Glendhill, K., Moore, K.R., Jacobs, M, and Orrison, W.W., Jr., (eds.) 2000. Chapter 21. In Neuroimaging, pp. 252‐755. W.B. Saunders, Philadelphia.
   Mason, I., Aase, J.M., Orrison, W.W., Wicks, J.D., Seigel, R.S., and Bicknell, J.M. 1988. Familial cavernous Angiomas of the brain in an Hispanic family. Neurology 38:324‐326.
   Mitchell, D.G. 1999. MRI Principles, pp. 266‐267. W.B. Saunders, Philadelphia.
   Rigamonti, D., Drayer, B.P., Johnson, P.C., Hadley, M.N., Zabramski, J., and Spetzler, R.F. 1987. The MRI appearance of cavernous malformations (Angiomas). J. Neurosurgery 67:518‐524.
   Robinson, J.R., Awad, I.A., Little, J.R. 1991 Natural history of the cavernous angioma. J. Neurosurgery 75:709‐714.
   Shellock, F.G. 1996. Pocket Guide to MR Procedures and Metallic Objects. Lippincott‐Raven, Philadelphia.
   Tomlinson, F.H., Houser, O.W., Scheithauer, B.W., Sundt, T.M., Jr., Okozaki, H., and Parisa, J.E. 1994. Angiographically occult vascular malformations: A correlative study of features on magnetic resonance imaging and histological examination. Neurosurgery 34:792‐800.
   Wilson, C.B. 1992. Cryptic vascular malformations. Clinics Neurosurg. 38:49‐84.
Key References
   Fischbein, 2000. See above.
  These authors afford a current concise look at intracranial vascular malformations. In addition to imaging findings, they discuss etiology, clinical findings, treatment, complications, pearls and pitfalls.
   Shellock, 1996. See above.
  Covers a number of important patient management issues related to MR imaging, including recommended safety procedures, a list of metallic implants that have been tested for MR compatibility, and a list of other sources on MR safety.
GO TO THE FULL PROTOCOL:
PDF or HTML at Wiley Online Library