Monitoring Tumor Therapy

Annette O. Nusbaum1, Scott W. Atlas2

1 New York Presbyterian Hospital, New York, New York, 2 Stanford University Medical Center, Stanford, California
Publication Name:  Current Protocols in Magnetic Resonance Imaging
Unit Number:  Unit A3.5
DOI:  10.1002/0471142719.mia0305s00
Online Posting Date:  May, 2001
GO TO THE FULL TEXT: PDF or HTML at Wiley Online Library

Abstract

This unit presents the preferred protocol for imaging the brain following the institution of chemotherapy, radiation therapy, or surgery for brain tumors and specific modifications are discussed where necessary. The sequences described in this unit are based on a 1.5 T scanner (Echospeed GE Medical Systems), but can be expected to be equally applicable to other field strengths and scanners from other manufacturers.

     
 
GO TO THE FULL PROTOCOL:
PDF or HTML at Wiley Online Library

Table of Contents

  • Basic Protocol 1: Follow‐Up Post Surgery
  • Basic Protocol 2: Radiation Necrosis Versus Tumor Recurrence
  • Commentary
  • Literature Cited
  • Tables
     
 
GO TO THE FULL PROTOCOL:
PDF or HTML at Wiley Online Library

Materials

Basic Protocol 1: Follow‐Up Post Surgery

  Materials
  • Intravenous contrast agent (e.g., Magnevist, Omniscan, Prohance)
  • Normal saline (0.9% NaCl), sterile
GO TO THE FULL PROTOCOL:
PDF or HTML at Wiley Online Library

Figures

Videos

Literature Cited

Literature Cited
   Atlas, S.W. and Lavi, E. 1996. Intra‐axial brain tumors. In Magnetic Resonance Imaging of the Brain and Spine. 2nd Edition (S.W. Atlas, ed.). pp. 315‐422. Lippincott‐Raven, Philadelphia.
   Grossman, R.I., Hecht‐Leavitt, C.M., Evans, S.M., Lenkinski, R.E., Holland, G.A., Van Winkle, T.J., McGrath, J.T., Curran, W.J., Shetty, A., and Joseph, P.M. 1988. Experimental radiation injury: Combined MR imaging and spectroscopy. Radiology. 169:305‐309.
   Nelson, S.J., Vigneron, D.B., and Dillon, W.P. 1999. Serial evaluation of patients with brain tumors using volume MRI and 3D 1H MRSI. N.M.R. Biomed. 12:123‐138.
   Ricci, P.E., Pitt, A., Keller, P.J., Coons, S.W., and Heiserman, J.E. 2000. Effect of voxel position on single‐voxel MR spectroscopy findings. Am. J. Neuroradiol. 21:367‐374.
   Shellock, F.G. 1996. Pocket Guide to MR Procedures and Metallic Objects. Lippincott‐Raven, Philadelphia.
   Sijens, P.E., van den Bent, M.J., Nowak, P.J., van Dijk, P., and Ouderk, M. 1997. 1H chemical shift imaging reveals loss of brain tumor choline signal after administration of Gd‐contrast. Magn. Reson. Med. 37:222‐225.
   Taylor, J.S., Langston, J.W., Reddick, W.E., Wingsley, P.B., Ogg, R.J., Pui, M.H., Kun, L.E., Jenkins, J.J. 3rd, Chen, G., Ochs, J.J., Sanford, R.A., and Heideman, R.L. 1996. Clinical value of proton magnetic resonance spectroscopy for differentiating recurrent or residual brain tumor from delayed cerebral necrosis. Int. J. Radiat. Oncol. Biol. Phys. 36:1251‐1261.
GO TO THE FULL PROTOCOL:
PDF or HTML at Wiley Online Library