Danial K. Hallam1, Noriko Salamon‐Muramaya2

1 University of Washington, Seattle, Washington, 2 Northwestern University, Chicago, Illinois
Publication Name:  Current Protocols in Magnetic Resonance Imaging
Unit Number:  Unit A5.3
DOI:  10.1002/0471142719.mia0503s06
Online Posting Date:  November, 2002
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This unit presents specific protocols intended to maximize the contribution of MRI to the clinical evaluation of dementia. Each protocol has, as its foundation, a whole‐brain screen designed to evaluate for treatable causes of dementia. Reflecting the frequent overlap of vascular disease with dementing illness, the screening protocol also serves as an optimal evaluation of the patient with suspected vascular dementia. Additional sequences or modifications are then used to answer specific clinical questions. The parameters given here are derived from experience at 1.5 T and may need to be altered slightly depending on the field strength and the equipment manufacturer.

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Table of Contents

  • Basic Protocol 1: Vascular Dementia
  • Basic Protocol 2: Alzheimer's Disease
  • Basic Protocol 3: Huntington's Disease
  • Basic Protocol 4: Parkinson's Disease
  • Commentary
  • Figures
  • Tables
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Key References
   Shellock and Kanal, 1996. See above.
  Covers a number of important patient management issues related to MR imaging, including recommended safety procedures, a list of metallic implants that have been tested for MR compatibility, and a list of other sources on MR safety.
   Terry, R.D., Katzman, R., and Bick, K.L. 1999. Alzheimer Disease, 2nd Edition. Lippincott Williams & Wilkins, Philadelphia.
  A current review of the major aspects of Alzheimer's disease including clinical, epidemiologic, structural, imaging, chemical, genetic, and molecular.
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