Quality Assurance for Clinical fMRI

Keith R. Thulborn1, Denise Davis1

1 University of Illinois at Chicago, Chicago, Illinois
Publication Name:  Current Protocols in Magnetic Resonance Imaging
Unit Number:  Unit A6.2
DOI:  10.1002/0471142719.mia0602s00
Online Posting Date:  May, 2001
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Abstract

The functional MRI (fMRI) procedure has several sources of variance that determine the success of the examination. These include the scanner, patient, and paradigm. As blood oxygenation level dependent (BOLD) contrast is a small effect, high signal‐to‐noise performance is mandatory. Because the preparation of a functional activation map requires averaging multiple images over time, the scanner must produce high temporal stability of the signal intensity. This unit presents the for achieving scanner stability. There are many determinants of such performance but not all possibilities need to be checked separately. An adequate approach has been to verify total system performance under the conditions of a functional MRI study on a phantom. This testing is done daily prior to patient studies.

     
 
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Table of Contents

  • Basic Protocol 1: Scanner Stability
  • Commentary
  • Literature Cited
  • Figures
  • Tables
     
 
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Materials

Basic Protocol 1: Scanner Stability

  Materials
  • Spherical phantom in loader with doped water, 16‐cm diameter
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Figures

Videos

Literature Cited

Literature Cited
   Thulborn, K.R. 1999. Quality assurance in clinical and research echo‐planar functional MRI. In Medical Radiology: Diagnostic Imaging and Radiation Oncology. Functional MRI (C. Moonen and P. Bandettini, eds.) pp. 337‐345. Springer‐Verlag, Berlin.
   Thulborn, K.R. and Gisbert, A. 2000. Clinical Applications of Mapping Neurocognitive Processes in the Human Brain with Functional MRI. (P. Matthews and P. Jezzard, eds.) Oxford University Press, Oxford. In press.
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