Recent Progress in DNA Origami Technology

Masayuki Endo1, Hiroshi Sugiyama2

1 Institute for Integrated Cell‐Material Sciences (iCeMS), Kyoto University, Kyoto, Japan, 2 Department of Chemistry, Graduate School of Science, Kyoto University, Kyoto, Japan
Publication Name:  Current Protocols in Nucleic Acid Chemistry
Unit Number:  Unit 12.8
DOI:  10.1002/0471142700.nc1208s45
Online Posting Date:  June, 2011
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DNA origami is an emerging technology for designing defined two‐dimensional DNA nanostructures. In this review, we focus on and describe several types of DNA origami‐related studies, as follows: (1) programmed DNA origami assembly, (2) DNA origami‐templated molecular assembly, (3) design and construction of various three‐dimensional DNA origami structures, (4) programmed functionalization of DNA origami and combination with top‐down nanotechnology, (5) single molecular observation on a designed DNA origami, and (6) DNA nanomachines working on a DNA origami. Curr. Protoc. Nucleic Acid Chem. 45:12.8.1‐12.8.19. © 2011 by John Wiley & Sons, Inc.

Keywords: DNA origami; designed nanospace; single molecular analysis; DNA nanomachine; high‐speed AFM

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Table of Contents

  • Introduction
  • Two‐Dimensional DNA Origami
  • Conclusion and Prospects
  • Literature Cited
  • Figures
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Literature Cited

Literature Cited
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