Electrophysiological Techniques

Mike Williams1

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Publication Name:  Current Protocols in Pharmacology
Unit Number:  Unit 11.0
DOI:  10.1002/0471141755.ph1100s39
Online Posting Date:  December, 2007
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Abstract

     
 
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Table of Contents

  • Introduction
  • Literature Cited
     
 
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Materials

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Figures

Videos

Literature Cited

Literature Cited
   Arneric, S.P., Holladay, M.W. and Williams, M. 2007. Neuronal nicotinic receptors: A perspective on two decades of drug discovery research. Biochem. Pharmacol. 74:1092‐1101.
   Ashcroft, F.M. 2000. Ion Channels and Disease: Channelopathies. Academic Press, San Diego.
   Barnard, E.A., Skolnick, P., Olsen, R.W., Mohler, H., Siegart, W., Biggio, G., Braestrup, C., Bateson, A.N., and Langer, S.Z. 1998. International Union of Pharmacology XV: Subtypes of γ‐aminobutyric acidA receptors. Pharmacol. Rev. 50:291‐314.
   Braestrup, C. and Squires, R.F. 1978. Brain specific benzodiazepine receptors. Br. J. Psychiatr. 133:249‐260.
   Breining, S.R., Mazrov, A.A., and Miller, C.H. 2005. Neuronal nicotinic acetylcholine receptor modulators: Recent advances and therapeutic potential. Ann. Rep. Med. Chem. 40:3‐16.
   Christopoulos, A. 2002. Allosteric binding sites on cell‐surface receptors: Novel targets for drug discovery. Nature Rev. Drug Discov. 1:198‐210.
   Daly, J.W., Garraffo, H.M., Spander, T.F., Decker, M.W., Sullivan, J.P., and Williams, M. 2000. Alkaloids from frog skin: The discovery of epibatidine and the potential for developing novel non‐opioid analgesics. Natural Prod. Rep. 17:131‐135.
   Doyle, D.A., Cabral, J.M., Pfuetzner, R.A., Kuo, A., Gulbis, J.M., Cohen, S.L., Cahit, B.T., and MacKinnon, R. 1998. The structure of the potassium channel: Molecular basis of K+ conduction and selectivity. Science 280:69‐77.
   Fermini, B. and Fossa, A.A. 2003. The impact of drug‐induced QT interval prolongation on drug discovery and development. Nature Rev. Drug Discov. 2:439–447.
   Le Novère, N. and Changeux, J.P. 1995. Molecular evolution of the nicotinic acetylcholine receptor: An example of multigene family in excitable cells. J. Mol. Evol. 40:155–172.
   Lloyd, G.K. and Williams, M. 2000. Perspective in pharmacology: Neuronal nicotinic receptors as novel drug targets. J. Pharmacol. Exp. Ther. 292:461–467.
   Möhler, H. and Okada, T. 1978. The benzodiazepine receptor in normal and pathological human brain. Br. J. Psychiatr. 133:261–268.
   Noda, M., Takahashi, H., Tanabe, T., Toyosato, M., Furutani, M., Hirose, T., Asai, M., Inayama, S., Miyata, T., and Numa, S. 1982. Primary structure of a subunit precursor of Torpedo californica acetylcholine receptor deduced from cDNA sequence. Nature 299:793–797.
   Williams, M., and Raddatz, R. 2007. Receptors as drug targets. In Short Protocols in Pharmacology and Drug Discovery. (S.J. Enna, M. Williams, J.W. Ferkany, T. Kenakin and R.D. Porsolt, eds.) pp. 2‐1–2‐20. John Wiley & Sons, Hoboken, N.J.
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