Enzyme Nomenclature


Publication Name:  Current Protocols in Pharmacology
Unit Number:  Appendix 1A
DOI:  10.1002/0471141755.pha01as00
Online Posting Date:  May, 2001
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Abstract

This appendix describes the “EC” (Enzyme Commission) numbering convention, starting with how enzymes are first grouped into one of six classes according to the reaction catalyzed, and then subclassified in terms of the donors, then acceptors, and then the actual enzyme reaction. An example is given of the major sub‐subclasses of oxidoreductases along with many hundreds of enzymes in this class. Because this classification procedure came into being when there was little knowledge of enzyme structure and when protein cloning and expression was in its infancy, enzymes are classified according to their function. This is unlike receptor classification, which relies on structure and coupling.

     
 
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Table of Contents

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Literature Cited

Literature Cited
   Dixon, M., and Webb, E.C. 1979. Enzymes, 3rd Ed. Academic Press, New York.
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