Neurobehavioral Testing in Humans

W. Kent Anger1, Diane S. Rohlman1, Daniel Storzbach1

1 Oregon Health Sciences University, Portland, Oregon
Publication Name:  Current Protocols in Toxicology
Unit Number:  Unit 11.7
DOI:  10.1002/0471140856.tx1107s02
Online Posting Date:  May, 2001
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The evaluation of the effects of chemical exposures on humans is a worldwide concern, and most chemicals have not been evaluated for neurotoxic effect. Human neurobehavioral research or clinical evaluations of populations exposed to chemicals must be carefully planned and structured. This unit describes the steps required to create such a study, select the appropriate measures, and evaluate the results.

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Table of Contents

  • Study Design: Defining the Goal of the Research
  • Test Selection: Building a Battery
  • Preliminary Data Analysis Plan and Power Analysis
  • Implications of Demographic Factors
  • Test Details: The Parameters
  • Test Setting
  • Study Details: Protocols
  • Study Details: Procedures
  • Data Management
  • Data Analysis
  • Commentary
  • Literature Cited
  • Figures
  • Tables
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Literature Cited

Literature Cited
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   Amler, R.W., Anger, W.K., and Sizemore, O.J. 1995. Adult Environmental Neurobehavioral Test Battery (Training Manual). US Department of Health and Human Services, Public Health Service, Agency for Toxic Substances and Disease Registry, Atlanta, Ga.
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