Toxicity Testing in Chemical Safety Evaluation

James S. Bus1

1 The Dow Chemical Company, Midland, Michigan
Publication Name:  Current Protocols in Toxicology
Unit Number:  Unit 19.2
DOI:  10.1002/0471141755.tx1902s31
Online Posting Date:  February, 2007
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Abstract

The modern era of chemistry has resulted in dramatic improvements in the overall human condition. In addition to new pharmaceuticals, modern chemistry has brought with it enormous health and social benefits Introduction of chemistry‐based technologies, however, has also been clearly associated with potential human health risks. The dramatic increase in pharmaceutical and chemical technologies in the post World War II era, coupled with associated examples of demonstrated human toxicity, led to development and application of an expanded and standardized battery of animal and other toxicity tests designed to characterize the potential hazards and risks associated with chemical exposures. This unit discusses the current approach to industrial chemical and pesticide toxicity testing.

Keywords: Toxicity testing; Industrial chemical; Pesticides; EPA guidelines

     
 
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Table of Contents

  • Industrial Chemical and Pesticide Toxicity Tests
  • Tables
     
 
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Materials

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Literature Cited

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