Strategies for Bioactive Small Molecule Discovery

Listings: 1-20   21-38
Alphabetical     Date
Multiplexing High‐Content Flow (HCF) and Quantitative High‐Throughput Screening (qHTS) to Identify Compounds Capable of Decreasing Cell Viability, Activating Caspase 3/7, Expressing Annexin V, and Changing Mitochondrial Membrane Integrity
Lesley A. Mathews, Jonathan M. Keller, Crystal McKnight, Sam Michael, Paul Shinn, Dongbo Liu, Louis M. Staudt, Craig J. Thomas, Marc Ferrer
Published online: October 2013
Profiling Native Kinases by Immuno‐Assisted Activity‐Based Profiling
Eric Okerberg, Ann Shih, Heidi Brown, Senait Alemayehu, Arwin Aban, Tyzoon K. Nomanbhoy
Published online: October 2013
In Vivo Rapid Assessment of Compound Exposure (RACE) for Profiling the Pharmacokinetics of Novel Chemical Probes
Danielle McAnally, Michael Vicchiarelli, Khandaker Siddiquee, Layton H. Smith
Published online: December 2012
Selecting, Acquiring, and Using Small Molecule Libraries for High‐Throughput Screening
Sivaraman Dandapani, Gerard Rosse, Noel Southall, Joseph M. Salvino, Craig J. Thomas
Published online: September 2012
Parallel Chemistry in the 21st Century
Alan Long
Published online: September 2012
In Situ Hybridization Assay‐Based Small‐Molecule Screening in Zebrafish
Lili Jing, Ellen M. Durand, Catherine Ezzio, Stephanie M. Pagliuca, Leonard I. Zon
Published online: June 2012
High‐Throughput RT‐PCR for Small‐Molecule Screening Assays
Joshua A. Bittker
Published online: March 2012
Target Identification Using Drug Affinity Responsive Target Stability (DARTS)
Brett Lomenick, Gwanghyun Jung, James A. Wohlschlegel, Jing Huang
Published online: December 2011
Compound Management: Guidelines for Compound Storage, Provision, and Quality Control
Sue Holland‐Crimmin, Paul Gosnell, Chad Quinn
Published online: September 2011
Storage and Handling Guidelines for Custom Peptides
Amanda Turner, Katy Radburn‐Smith, Adeel Mushtaq, Linda Tan
Published online: April 2011
Parallel High‐Throughput Automated Assays to Measure Cell Growth and Beta‐Galactosidase Reporter Gene Expression in the Yeast Saccharomyces cerevisiae
Andrew D. Napper, Nuzhat Motlekar, Rogerio Alves de Almeida, Graham D. Pavitt
Published online: January 2011
Small‐Molecule Library Synthesis on Silicon‐Functionalized SynPhase Lanterns
Jeremy R. Duvall, Anita Vrcic, Lisa A. Marcaurelle
Published online: July 2010
Untargeted Metabolomics
Nawaporn Vinayavekhin, Alan Saghatelian
Published online: April 2010
Listings: 1-20   21-38