Small Molecule Screening and Analysis
Overview of Determination of Biopharmaceutical Properties for Development Candidate Selection
Mehran Yazdanian
Published online: March 2013
Mehran Yazdanian
Published online: March 2013
A High‐Throughput Screening Method for Identification of Inhibitors of the Deubiquitinating Enzyme USP14
Byung‐Hoon Lee, Daniel Finley, Randall W. King
Published online: December 2012
Byung‐Hoon Lee, Daniel Finley, Randall W. King
Published online: December 2012
Proteolytic Fingerprinting of Complex Biological Samples Using Combinatorial Libraries of Fluorogenic Probes
Kalyani Jambunathan, Douglas S. Watson, Krishna Kodukula, Amit K. Galande
Published online: November 2012
Kalyani Jambunathan, Douglas S. Watson, Krishna Kodukula, Amit K. Galande
Published online: November 2012
Selecting, Acquiring, and Using Small Molecule Libraries for High‐Throughput Screening
Sivaraman Dandapani, Gerard Rosse, Noel Southall, Joseph M. Salvino, Craig J. Thomas
Published online: September 2012
Sivaraman Dandapani, Gerard Rosse, Noel Southall, Joseph M. Salvino, Craig J. Thomas
Published online: September 2012
LC‐MS Data Processing with MAVEN: A Metabolomic Analysis and Visualization Engine
Michelle F. Clasquin, Michelle F. Clasquin, Eugene Melamud, Eugene Melamud, Joshua D. Rabinowitz
Published online: March 2012
Michelle F. Clasquin, Michelle F. Clasquin, Eugene Melamud, Eugene Melamud, Joshua D. Rabinowitz
Published online: March 2012
High‐Throughput RT‐PCR for Small‐Molecule Screening Assays
Joshua A. Bittker
Published online: March 2012
Joshua A. Bittker
Published online: March 2012
The Combined Use of the Thermofluor Assay and ThermoQ Analytical Software for the Determination of Protein Stability and Buffer Optimization as an Aid in Protein Crystallization
Kevin Phillips, Andres Hernandez de la Peña
Published online: April 2011
Kevin Phillips, Andres Hernandez de la Peña
Published online: April 2011
Storage and Handling Guidelines for Custom Peptides
Amanda Turner, Katy Radburn‐Smith, Adeel Mushtaq, Linda Tan
Published online: April 2011
Amanda Turner, Katy Radburn‐Smith, Adeel Mushtaq, Linda Tan
Published online: April 2011
Nucleic Acid Programmable Protein Arrays: Versatile Tools for Array‐Based Functional Protein Studies
Shane Miersch, Joshua LaBaer
Published online: April 2011
Shane Miersch, Joshua LaBaer
Published online: April 2011
Quantification of Allosteric Interactions at G Protein–Coupled Receptors Using Radioligand Binding Assays
Katie Leach, Patrick M. Sexton, Arthur Christopoulos
Published online: March 2011
Katie Leach, Patrick M. Sexton, Arthur Christopoulos
Published online: March 2011
Overview of Receptor Allosterism
Karen J. Gregory, Patrick M. Sexton, Arthur Christopoulos
Published online: December 2010
Karen J. Gregory, Patrick M. Sexton, Arthur Christopoulos
Published online: December 2010
Measuring Receptor Target Coverage: A Radioligand Competition Binding Protocol for Assessing the Association and Dissociation Rates of Unlabeled Compounds
David A. Sykes, Mark R. Dowling, Steven J. Charlton
Published online: September 2010
David A. Sykes, Mark R. Dowling, Steven J. Charlton
Published online: September 2010
The STINT‐NMR Method for Studying In‐cell Protein‐Protein Interactions
David S. Burz, Alexander Shekhtman
Published online: August 2010
David S. Burz, Alexander Shekhtman
Published online: August 2010
In Vitro Selection of RNA Aptamers to a Small Molecule Target
Vlad Codrea, Michelle Hayner, Bradley Hall, Sulay Jhaveri, Andrew Ellington
Published online: March 2010
Vlad Codrea, Michelle Hayner, Bradley Hall, Sulay Jhaveri, Andrew Ellington
Published online: March 2010
Generation of Designer Receptors Exclusively Activated by Designer Drugs (DREADDs) Using Directed Molecular Evolution
Ying Pei, Shuyun Dong, Bryan L. Roth
Published online: January 2010
Ying Pei, Shuyun Dong, Bryan L. Roth
Published online: January 2010
Fluorescence Polarization (FP) Assays for Monitoring Peptide‐Protein or Nucleic Acid‐Protein Binding
Nathan J. Moerke
Published online: December 2009
Nathan J. Moerke
Published online: December 2009
Target Identification by Diazirine Photo‐Cross‐Linking and Click Chemistry
Andrew L. MacKinnon, Jack Taunton, Jack Taunton
Published online: December 2009
Andrew L. MacKinnon, Jack Taunton, Jack Taunton
Published online: December 2009
High‐Throughput Cytotoxicity Screening by Propidium Iodide Staining
Bruce S. Edwards, Irena Ivnitski‐Steele, Susan M. Young, Virginia M. Salas, Larry A. Sklar
Published online: July 2007
Bruce S. Edwards, Irena Ivnitski‐Steele, Susan M. Young, Virginia M. Salas, Larry A. Sklar
Published online: July 2007



