Drug Discovery Technologies

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A Real‐Time Image‐Based Approach to Distinguish and Discriminate Apoptosis from Necrosis
Asha Lekshmi, Shankara Narayanan Varadarajan, Santhik Subhasingh Lupitha, Mydhily Nair, Aneesh Chandrasekharan, T.R. Santhoshkumar
Published online: February 2018
Overview of microRNA Modulation in Analgesic Research
Sujay Ramanathan, Botros B. Shenoda, Seena K. Ajit
Published online: December 2017
In Vitro Validation of miRNA‐Mediated Gene Expression Linked to Drug Metabolism
Botros B. Shenoda, Sujay Ramanathan, Seena K. Ajit
Published online: December 2017
In Vitro Assays for the Functional Characterization of the Dopamine Transporter (DAT)
Shaili Aggarwal, Ole V. Mortensen
Published online: December 2017
High‐Throughput Screening of HECT E3 Ubiquitin Ligases Using UbFluor
Peter K. Foote, David T. Krist, Alexander V. Statsyuk
Published online: September 2017
Overview of Methods and Strategies for Conducting Virtual Small Molecule Screening
Xavier Fradera, Kerim Babaoglu
Published online: September 2017
Rodent Test of Attention and Impulsivity: The 5‐Choice Serial Reaction Time Task
Guy A. Higgins, Leo B. Silenieks
Published online: September 2017
All‐Optical Electrophysiology for Disease Modeling and Pharmacological Characterization of Neurons
Christopher A. Werley, Ted Brookings, Hansini Upadhyay, Luis A. Williams, Owen B. McManus, Graham T. Dempsey
Published online: September 2017
Protein‐Lipid Interaction by Fluorescence (PLIF) to Characterize and Screen for Inhibitors of Protein‐Phosphoinositide Interactions
Laurie Ceccato, Mélanie Mansat, Bernard Payrastre, Frédérique Gaits‐Iacovoni, Julien Viaud
Published online: August 2017
Bioluminescence Resonance Energy Transfer (BRET)‐Based Synthetic Sensor Platform for Drug Discovery
Jongchan Woo, Jason Hong, Savithramma P. Dinesh‐Kumar
Published online: April 2017
The Quantitative Characterization of Functional Allosteric Effects
Terry Kenakin
Published online: March 2017
Biomarkers—A General Review
Jeffrey K. Aronson, Robin E. Ferner
Published online: March 2017
Detection of Receptor Heteromerization Using In Situ Proximity Ligation Assay
Ivone Gomes, Salvador Sierra, Lakshmi A. Devi
Published online: December 2016
Stability of Drugs, Drug Candidates, and Metabolites in Blood and Plasma
Gregory A. Reed
Published online: December 2016
Overview on Research and Clinical Applications of Optogenetics
Chris Towne, Kimberly R. Thompson
Published online: December 2016
Pica in Rats as a Preclinical Model of Emesis
T. Gregg Davis
Published online: October 2016
In Vitro Drug Metabolism Using Liver Microsomes
Kathleen M. Knights, David M. Stresser, John O. Miners, Charles L. Crespi
Published online: September 2016
Combinatorial Library Screening Coupled to Mass Spectrometry to Identify Valuable Cyclic Peptides
Silvia A. Camperi, Silvana L. Giudicessi, María C. Martínez‐Ceron, Juan M. Gurevich‐Messina, Soledad L. Saavedra, Gerardo Acosta, Osvaldo Cascone, Rosa Erra‐Balsells, Fernando Albericio
Published online: June 2016
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