Pharmacokinetics/ADME

Listings: 1-20   21-25
Alphabetical     Date
Predicting Drug‐Induced QT Prolongation and Torsades de Pointes: A Review of Preclinical Endpoint Measures
Claire Townsend, Barry S. Brown
Published online: June 2013
Overview of Determination of Biopharmaceutical Properties for Development Candidate Selection
Mehran Yazdanian
Published online: March 2013
In Vivo Rapid Assessment of Compound Exposure (RACE) for Profiling the Pharmacokinetics of Novel Chemical Probes
Danielle McAnally, Danielle McAnally, Michael Vicchiarelli, Khandaker Siddiquee, Layton H. Smith, Layton H. Smith
Published online: December 2012
Guidelines for the Care and Use of Laboratory Animals in Biomedical Research
Susan Jones‐Bolin
Published online: December 2012
The Vesicular Transport Assay: Validated In Vitro Methods to Study Drug‐Mediated Inhibition of Canalicular Efflux Transporters ABCB11/BSEP and ABCC2/MRP2
Krisztina Herédi‐Szabó, Emese Kis, Peter Krajcsi
Published online: November 2012
Membrane Vesicle ABC Transporter Assays for Drug Safety Assessment
Carlo J. van Staden, Ryan E. Morgan, Bharath Ramachandran, Yuan Chen, Paul H. Lee, Hisham K. Hamadeh
Published online: November 2012
Selecting, Acquiring, and Using Small Molecule Libraries for High‐Throughput Screening
Sivaraman Dandapani, Gerard Rosse, Noel Southall, Joseph M. Salvino, Craig J. Thomas
Published online: September 2012
Assessment of P‐Glycoprotein Substrate and Inhibition Potential of Test Compounds in MDR1‐Transfected MDCK Cells
Kevin C. L. Lam, Ganesh Rajaraman
Published online: September 2012
Assessment of the Time‐Dependent Inhibition (TDI) Potential of Test Compounds with Human Liver Microsomes by IC50 Shift Method Using a Nondilution Approach
Lian de Ron, Ganesh Rajaraman
Published online: September 2012
Overview of Drug Product Development
Padma Narayan
Published online: December 2011
Measuring Receptor Target Coverage: A Radioligand Competition Binding Protocol for Assessing the Association and Dissociation Rates of Unlabeled Compounds
David A. Sykes, Mark R. Dowling, Steven J. Charlton
Published online: September 2010
The Ussing Chamber and Measurement of Drug Actions on Mucosal Ion Transport
David R. Brown, Scott M. O’Grady
Published online: June 2008
Cytochrome P450 Inhibition Assays Using Traditional and Fluorescent Substrates
Elsa Paradise, Prasoon Chaturvedi, Elena Ter‐Ovanesyan
Published online: December 2007
Overview of Pharmacogenetics
David A. Katz
Published online: March 2007
Determination of Compound Binding to Plasma Proteins
Natasha Dow
Published online: October 2006
In Vitro Species Comparisons and Metabolite Identification
Paul Dow
Published online: October 2006
Overview of Pharmacokinetics
Lisa D. Aimone
Published online: October 2005
Hepatic Clearance and Drug Metabolism Using Isolated Perfused Rat Liver
Yong Liu, Steven J. Weber, Emmanuel T. Onua
Published online: October 2004
Uptake Studies for Evaluating Activity of Efflux Transporters in a Cell Line Representative of the Blood‐Brain Barrier
Peter S. Silverstein, D. Nedra Karunaratne, Kenneth L. Audus
Published online: February 2004
In Vitro Drug Metabolism Using Liver Microsomes
Jeanette R. Hill
Published online: February 2004
Listings: 1-20   21-25