Preclinical Models of Disease

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Genetic and Pharmacologic Models for Type 1 Diabetes
Edward H. Leiter, Andrew Schile
Published online: March 2013
Cigarette Smoke Exposure as a Model of Inflammation Associated with COPD
Suffwan Eltom, Christopher Stevenson, Mark A. Birrell
Published online: March 2013
Patient‐Derived Models of Human Breast Cancer: Protocols for In Vitro and In Vivo Applications in Tumor Biology and Translational Medicine
Yoko S. DeRose, Keith M. Gligorich, Guoying Wang, Ann Georgelas, Paulette Bowman, Samir J. Courdy, Alana L. Welm, Bryan E. Welm
Published online: March 2013
Discovery of Biologically Active Oncologic and Immunologic Small Molecule Therapies using Zebrafish: Overview and Example of Modulation of T Cell Activation
Nikolaus S. Trede, William Heaton, Suzanne Ridges, Hossein Sofla, Matthew Cusick, David Bearss, David Jones, Robert S. Fujinami
Published online: March 2013
Blast Traumatic Brain Injury in the Rat Using a Blast Overpressure Model
Angela M. Yarnell, Michael C. Shaughness, Erin S. Barry, Stephen T. Ahlers, Richard M. McCarron, Neil E. Grunberg
Published online: January 2013
Water Maze Testing to Identify Compounds for Cognitive Enhancement
Gregory M. Rose, Wayne B. Rowe
Published online: December 2012
Overview of Animal Models of Obesity
Thomas A. Lutz, Stephen C. Woods
Published online: September 2012
Models of Affective Illness: Chronic Mild Stress in the Rat
Mariusz Papp
Published online: June 2012
Measuring Altered Disposition of Xenobiotics in Experimental Models of Liver Disease
Rhiannon N. Hardwick, Nathan J. Cherrington
Published online: May 2012
Diet‐Induced Models of Obesity (DIO) in Rodents
Didier Bagnol, Hussien A. Al‐Shamma, Dominic Behan, Kevin Whelan, Andrew J. Grottick
Published online: April 2012
Models of Neurological Disease (Substance Abuse): Self‐Administration in Monkeys
Donna M. Platt, Galen Carey, Roger D. Spealman
Published online: March 2012
Pentylenetetrazol (PTZ) Kindling Model of Epilepsy
Ashish Dhir
Published online: January 2012
Pre‐Clinical Mouse Models of Primary and Metastatic Pleural Cancers of the Lung and Breast and the Use of Bioluminescent Imaging to Monitor Pleural Tumor Burden
Elliot L. Servais, Christos Colovos, Stefan S. Kachala, Prasad S. Adusumilli
Published online: September 2011
Automated Three‐Chambered Social Approach Task for Mice
Mu Yang, Jill L. Silverman, Jacqueline N. Crawley
Published online: July 2011
Animal Models of Systemic Lupus Erythematosus (SLE) and Ex Vivo Assay Design for Drug Discovery
Matthew M. Seavey, Lily D. Lu, Kristine L. Stump
Published online: June 2011
Rodent Models of Depression: Forced Swim and Tail Suspension Behavioral Despair Tests in Rats and Mice
Vincent Castagné, Paul Moser, Sylvain Roux, Roger D. Porsolt
Published online: April 2011
Ethical Considerations in Mouse Experiments
Bernard Baertschi, Marcel Gyger
Published online: March 2011
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