Current Protocols in Mouse Biology

Editors & Contributors

Editors & Contributors

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EDITORIAL BOARD

Johan Auwerx
Ecole Polytechnique Fédérale de Lausanne

Susan L. Ackerman
The Jackson Laboratory

Stephen D. Brown
Harwell Science and Innovation Campus, UK

Monica Justice
Baylor College of Medicine

David D. Moore
Baylor College of Medicine

Joseph Nadeau
Pacific Northwest Research Institute

CONTRIBUTORS

Naji N. Abumrad
Department of Surgery
Vanderbilt University School of Medicine
Nashville, Tennessee and
Diabetes Research Training Center
Vanderbilt University School of Medicine
Nashville, Tennessee

Cristina Antal
Mouse Clinical Institute
Illkirch, France and
Institut d’Histologie, Faculté de Médecine
Strasbourg, France

Carina Arvidsson
Department of Molecular and Clinical Medicine
Sahlgrenska Center for Cardiovascular and Metabolic Research/Wallenberg Laboratory
University of Gothenburg
Gothenburg, Sweden

Johan Auwerx
Institut Clinique de la Souris (ICS)
Illkirch, France and
Ecole Polytechnique Fédérale de Lausanne
Lausanne, Switzerland

Abdelkader Ayadi
Institut Clinique de la Souris (ICS)
Illkirch, France

Fredrik Bäckhed
Department of Molecular and Clinical Medicine
Sahlgrenska Center for Cardiovascular and Metabolic Research/Wallenberg Laboratory
University of Gothenburg
Gothenburg, Sweden

Bernard Baertschi
Institute for Biomedical Ethics
University of Geneva
Geneva, Switzerland

Gareth T. Banks
Neurobehavioural Genetics
MRC Harwell
Harwell Science and Innovation Campus
Oxfordshire, United Kingdom

Isabelle Barde
School of Life Sciences and “Frontiers in Genetics” National Program
Ecole Polytechnique Fédérale de Lausanne (EPFL)
Lausanne, Switzerland

Duncan Bassett
Molecular Endocrinology Group
Department of Medicine
Imperial College London
Hammersmith Campus
London, United Kingdom

Fernando J. Benavides
The University of Texas M.D. Anderson Cancer Center
Science Park-Research Division
Smithville, Texas

David E. Bergstrom
The Jackson Laboratory
Bar Harbor, Maine

Marie-Christine Birling
Institut Clinique de la Souris (ICS)
Illkirch, France

Gonzalo Blanco
Department of Biology
University of York
York, United Kingdom

Kelli L. Boyd
Department of Pathology
Vanderbilt University School of Medicine
Nashville, Tennessee and
Mouse Metabolic Phenotyping Center
Vanderbilt University School of Medicine
Nashville, Tennessee

Simon P. Brooks
The Brain Repair Group
School of Biosciences
Cardiff University
Cardiff, Wales, United Kingdom

J.T. Brown
Pfizer Applied Neurophysiology Group
School of Physiology and Pharmacology
University of Bristol
Bristol, United Kingdom

Gemma Brufau
Department of Pediatrics
Center for Liver, Digestive, and Metabolic Diseases
University Medical Center Groningen
University of Groningen
Groningen, The Netherlands

Carol J. Bult
The Jackson Laboratory
Bar Harbor, Maine

Tanya Burkholder
Division of Veterinary Resources
Office of Research Services
National Institutes of Health
Bethesda, Maryland

Rachel A. Burt
Molecular Medicine Division
The Walter and Eliza Hall Institute of Medical Research
Parkville, Australia,
Department of Medical Biology
The University of Melbourne
Parkville, Australia,
Hearing Co-Operative Research Centre
Melbourne, Australia, and
Murdoch Children’s Research Institute
Royal Children’s Hospital
Parkville, Australia

Marina R. Carpinelli
Molecular Medicine Division
The Walter and Eliza Hall Institute of Medical Research
Parkville, Australia,
Department of Medical Biology
The University of Melbourne
Parkville, Australia,
Hearing Co-Operative Research Centre
Melbourne, Australia, and
Murdoch Children’s Research Institute
Royal Children’s Hospital
Parkville, Australia

Pierre Chambon
Institut de Génétique et de Biologie Moléculaire et Cellulaire
Université de Strasbourg, and Collége de France
Illkirch, France

Nathalie Chartoire
Institut Clinique de la Souris (ICS)
Illkirch, France

Philippe Choquet
Laboratoire d’Imagerie Préclinique
Service de Biophysique et Médecine Nucléaire
Hopitaux Universitaires de Strasbourg
Strasbourg, France

André Constantinesco
Laboratoire d’Imagerie Préclinique
Service de Biophysique et Médecine Nucléaire
Hopitaux Universitaires de Strasbourg
Strasbourg, France

Peter I. Croucher
The Mellanby Centre for Bone Research
Department of Human Metabolism
University of Sheffield and
Sheffield, United Kingdom
Garvan Institute for Medical Research
Sydney, Australia

Francois Daubeuf
Laboratoire d’Innovation Thérapeutique
Faculté de Pharmacie
UMR7200 CNRS/Université de Strasbourg
Illkirch Cedex, France

Muriel T. Davisson
The Jackson Laboratory
Bar Harbor, Maine

Carlie J.M. de Vries
Department of Medical Biochemistry
Academic Medical Center
University of Amsterdam
Amsterdam, The Netherlands

Menno P.J. de Winther
Department of Medical Biochemistry
Academic Medical Center
University of Amsterdam
Amsterdam, The Netherlands

Francesco J. DeMayo
Department of Molecular and Cellular Biology
Baylor College of Medicine
Houston, Texas

Janet L. DeMayo
Department of Molecular and Cellular Biology
Baylor College of Medicine
Houston, Texas

Vivian deWaard
Department of Medical Biochemistry
Academic Medical Center
University of Amsterdam
Amsterdam, The Netherlands

Leah Rae Donahue
The Jackson Laboratory
Bar Harbor, Maine

Luis E. Donate
Spanish National Cancer Research Centre (CNIO)
Madrid, Spain

Charles J. Donnelly
The Jackson Laboratory
Bar Harbor, Maine

Stephen B. Dunnett
The Brain Repair Group
School of Biosciences
Cardiff University
Cardiff, Wales, United Kingdom

Christopher T. Esapa
MRC Mammalian Genetics Unit
MRC Harwell
Harwell Science and Innovation Campus
Oxfordshire, United Kingdom and
Academic Endocrine Unit
Nuffield Department of Clinical Medicine
University of Oxford
Oxford Centre for Diabetes, Endocrinology and Metabolism
Churchill Hospital Headington
Oxford, United Kingdom

Pascal Escher
IRO-Institute for Research in Ophthalmology
Sion, Switzerland and
Department of Ophthalmology
University of Lausanne
Lausanne, Switzerland

Holly Evans
The Mellanby Centre for Bone Research
Department of Human Metabolism
University of Sheffield
Sheffield, United Kingdom

Jérôme N. Feige
MusculoSkeletal Diseases
Novartis Institute for Biomedical Research
Basel, Switzerland

Cathy Fernandes
Social, Genetic and Developmental Psychiatry Centre
King’s College London
London, United Kingdom

Giséle Ferrand
Ecole Polytechnique Fédérale de Lausanne
Lausanne, Switzerland

Charmaine Foltz
Division of Veterinary Resources
Office of Research Services
National Institutes of Health
Bethesda, Maryland

L.H. Forsyth
School of Physiology and Pharmacology
University of Bristol
Bristol, United Kingdom

Paul Franken
Center for Integrative Genomics
University of Lausanne
Lausanne, Switzerland

Nelly Frossard
Laboratoire d’Innovation Thérapeutique
Faculté de Pharmacie
UMR7200 CNRS/Université de Strasbourg
Illkirch Cedex, France

Shumin Gao
The University of Medicine & Dentistry of New Jersey
New Jersey Medical School
Newark, New Jersey

Marion J.J. Gijbels
Department of Medical Biochemistry
Academic Medical Center
University of Amsterdam
Amsterdam, The Netherlands and
Department of Pathology and Department of Molecular Genetics
Cardiovascular Research Institute Maastricht
Maastricht University
Maastricht, The Netherlands

Christian Goetz
Laboratoire d’Imagerie Préclinique
Service de Biophysique et Médecine Nucléaire
Hopitaux Universitaires de Strasbourg
Strasbourg, France

Françoise Gofflot
Institut Clinique de la Souris (ICS)
Illkirch, France and
Université Catholique de Louvain
Life Science Institute
Louvain-la-Neuve, Belgium

Isabelle Goncalves da Cruz
Institut Clinique de la Souris (ICS)
Illkirch, France

Linda Greensmith
UCL Institute of Neurology
London, United Kingdom

Jacob B. Griffin
Roche Madison Inc.
Madison, Wisconsin

Albert K. Groen
Department of Pediatrics
Center for Liver, Digestive, and Metabolic Diseases
University Medical Center Groningen
University of Groningen
Groningen, The Netherlands and
Department of Laboratory Medicine
Center for Liver, Digestive, and Metabolic Diseases
University Medical Center Groningen
University of Groningen
Groningen, The Netherlands

Jean-Louis Guénet
Département de Biologie du Développement
Institut Pasteur
Paris, France

Marcel Gyger
EPFL—Center of Phenogenomics
Lausanne, Switzerland

Anna Hallén
Department of Molecular and Clinical Medicine
Sahlgrenska Center for Cardiovascular and Metabolic Research/Wallenberg Laboratory
University of Gothenburg
Gothenburg, Sweden

Svenja Hensler
Helmholtz Center Munich
Institute for Developmental Genetics
Munich, Germany and
Chair for Developmental Genetics
Technische Universität München
Munich, Germany

Yann Hérault
Mouse Clinical Institute
Illkirch, France and
Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC)
CNRS/INSERM/Université Louis Pasteur
Illkirch, France

David Ho
The University of Medicine & Dentistry of New Jersey
New Jersey Medical School
Newark, New Jersey

Chull Hong
The University of Medicine & Dentistry of New Jersey
New Jersey Medical School
Newark, New Jersey

Philip N. Howles
Department of Pathology and Laboratory Medicine
University of Cincinnati
Cincinnati, Ohio

Neil J. Ingham
Wellcome Trust Sanger Institute
Wellcome Trust Genome Campus
Hinxton, Cambridge, United Kingdom

M.W. Jones
School of Physiology and Pharmacology
University of Bristol
Bristol, United Kingdom

Bernadett Kalmar
UCL Institute of Neurology
London, United Kingdom

Eleanor Karlsson
Division of Veterinary Resources
Office of Research Services
National Institutes of Health
Bethesda, Maryland

Benjamin T. Kile
Cancer and Hematology Division
The Walter and Eliza Hall Institute of Medical Research
Parkville, Australia and
Department of Medical Biology
The University of Melbourne
Parkville, Australia

Alison B. Kohan
Department of Pathology and Laboratory Medicine
University of Cincinnati
Cincinnati, Ohio

Ralf Kühn
Helmholtz Center Munich
Institute for Developmental Genetics
Munich, Germany and
Chair for Developmental Genetics
Technische Universität München
Munich, Germany

David A. Largaespada
Department of Genetics, Cell Biology, and Development
University of Minnesota
Minneapolis, Minnesota,
Center for Genome Engineering
University of Minnesota
Minneapolis, Minnesota, and
Masonic Cancer Center
University of Minnesota
Minneapolis, Minnesota

Edward H. Leiter
The Jackson Laboratory
Bar Harbor, Maine

Michael T. Lewis
Lester and Sue Smith Breast Center
Baylor College of Medicine
Houston, Texas and
Department of Molecular and Cellular Biology and Department of Radiology
Baylor College of Medicine
Houston, Texas

Dongcai Liang
Department of Molecular and Cellular Biology
Baylor College of Medicine
Houston, Texas

C. Garry Linton
Division of Veterinary Resources
Office of Research Services
National Institutes of Health
Bethesda, Maryland

Guillermina Lozano
Department of Genetics
University of Texas MD Anderson Cancer Center
Houston, Texas

Pontus Lundberg
Department of Biomedicine
Experimental Hematology
University Hospital Basel
Basel, Switzerland

Esther Lutgens
Department of Medical Biochemistry
Academic Medical Center
University of Amsterdam
Amsterdam, The Netherlands and
Institute for Cardiovascular Prevention (IPEK)
Ludwig Maximilians University (LMU)
Munich, Germany

Bonnie L. Lyons
The Jackson Laboratory
Bar Harbor, Maine

Fabienne Marcelli
IRO-Institute for Research in Ophthalmology
Sion, Switzerland and
EPFL-Ecole Polytechnique Fédérale
Lausanne, Switzerland

Laurent Monassier
Laboratoire de Neurobiologie et Pharmacologie Cardiovasculaire
Université de Strasbourg
Strasbourg, France

Géraldine Morgane Mang
Center for Integrative Genomics
University of Lausanne
Lausanne, Switzerland

Stefan Marcaletti
MusculoSkeletal Diseases
Novartis Institute for Biomedical Research
Basel, Switzerland

Manuel Mark
Mouse Clinical Institute
Illkirch, France,
Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC)
CNRS/INSERM/Université Louis Pasteur
Illkirch, France and
Hôpital Universitaire de Strasbourg
Strasbourg, France

Daniel Metzger
Institut de Génétique et de Biologie Moléculaire et Cellulaire
Université de Strasbourg, and Collége de France
Illkirch, France

Hamid Meziane
Institut Clinique de la Souris (ICS)
Illkirch, France

Melanie Meyer
Helmholtz Center Munich
Institute for Developmental Genetics
Munich, Germany and
Chair for Developmental Genetics Technische Universität München
Munich, Germany

Michael S. Minett
Molecular Nociception Group
Wolfson Institute for Biomedical Research
University College London
London, United Kingdom and
London Pain Consortium
Kings College London
London, United Kingdom

Salvatore Modica
Institute of Food, Nutrition, and Health
ETH Zurich
Schwerzenbach, Switzerland

Branden Moriarty
Department of Genetics, Cell Biology, and Development
University of Minnesota
Minneapolis, Minnesota,
Center for Genome Engineering
University of Minnesota
Minneapolis, Minnesota, and
Masonic Cancer Center
University of Minnesota
Minneapolis, Minnesota

Antonio Moschetta
Laboratory of Lipid Metabolism and Cancer
Department of Translational Pharmacology
Consorzio Mario Negri Sud
Santa Maria Imbaro, Italy and
Clinica Medica “A. Murri”
Department of Internal and Public Medicine
University Aldo Moro of Bari
Bari, Italy

Francisca Mulero
Spanish National Cancer Research Centre (CNIO)
Madrid, Spain

Stéphanie Muller
Mouse Clinical Institute
Illkirch, France

Stefania Murzilli
Laboratory of Lipid Metabolism and Cancer
Department of Translational Pharmacology
Consorzio Mario Negri Sud
Santa Maria Imbaro, Italy

Patrick M. Nolan
Neurobehavioural Genetics
MRC Harwell
Harwell Science and Innovation Campus
Oxfordshire, United Kingdom

Sandra Offner
School of Life Sciences and “Frontiers in Genetics” National Program
Ecole Polytechnique Fédérale de Lausanne (EPFL)
Lausanne, Switzerland

Oskar Ortiz
Helmholtz Center Munich
Institute for Developmental Genetics
Munich, Germany

Abdel Mottalib Ouagazzal
Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC)
CNRS
UMR7104
Illkirch, France

Sudeepta Panda
Helmholtz Center Munich
Institute for Developmental Genetics
Munich, Germany and
Chair for Developmental Genetics
Technische Universität München
Munich, Germany

Jan Parker-Thornburg
Department of Biochemistry and Molecular Biology
University of Texas MD Anderson Cancer Center
Houston, Texas

Selina Pearson
Wellcome Trust Sanger Institute
Wellcome Trust Genome Campus
Hinxton, Cambridge, United Kingdom

Timothy R. Powell
Social, Genetic and Developmental Psychiatry Centre
King’s College London
London, United Kingdom

Kathryn Quick
Molecular Nociception Group
Wolfson Institute for Biomedical Research
University College London
London, United Kingdom and
London Pain Consortium
Kings College London
London, United Kingdom

Hannah G. Radley-Crabb
School of Anatomy and Human Biology
The University of Western Australia
Crawley, Australia

A.D. Randall
Pfizer Applied Neurophysiology Group
School of Physiology and Pharmacology
University of Bristol
Bristol, United Kingdom

Laura G. Reinholdt
The Jackson Laboratory
Bar Harbor, Maine

Richard R. Ribchester
Euan MacDonald Centre for Motor Neurone Disease Research
University of Edinburgh
Edinburgh, United Kingdom

Leonard C. Schalkwyk
Social, Genetic and Developmental Psychiatry Centre
King’s College London
London, United Kingdom

Andrew Schile
The Jackson Laboratory
Bar Harbor, Maine

Daniel F. Schorderet
IRO-Institute for Research in Ophthalmology
Sion, Switzerland,
Department of Ophthalmology
University of Lausanne
Lausanne, Switzerland, and
EPFL-Ecole Polytechnique Fédérale
Lausanne, Switzerland

Klaus Schughart
Department of Infection Genetics
Helmholtz Centre for Infection Research and University of Veterinary Medicine Hannover
Braunschweig, Germany

Manuel Serrano
Spanish National Cancer Research Centre (CNIO)
Madrid, Spain

Radek Skoda
Department of Biomedicine
Experimental Hematology
University Hospital Basel
Basel, Switzerland

Joanne M. Smith
Division of Veterinary Resources
Office of Research Services
National Institutes of Health
Bethesda, Maryland

Bart Staels
Université Lille Nord de France
Lille, France
Inserm, U1011
Lille, France
UDSL
Lille, France
Institut Pasteur de Lille
Lille, France

Karen P. Steel
Wellcome Trust Sanger Institute
Wellcome Trust Genome Campus
Hinxton, Cambridge, United Kingdom

Anne Tailleux
Université Lille Nord de France
Lille, France
Inserm, U1011
Lille, France
UDSL
Lille, France
Institut Pasteur de Lille
Lille, France

Rajesh V. Thakker
Academic Endocrine Unit
Nuffield Department of Clinical Medicine
University of Oxford
Oxford Centre for Diabetes, Endocrinology and Metabolism
Churchill Hospital Headington
Oxford, United Kingdom

Charles Thomas
Center of Phenogenomics (CPG)
Ecole Polytechnique Fédérale de Lausanne
Lausanne, Switzerland

Didier Trono
School of Life Sciences and “Frontiers in Genetics” National Program
Ecole Polytechnique Fédérale de Lausanne (EPFL)
Lausanne, Switzerland

Rebecca C. Trueman
The Brain Repair Group
School of Biosciences
Cardiff University
Cardiff, Wales, United Kingdom

Patrick Tso
Department of Pathology and Laboratory Medicine
University of Cincinnati
Cincinnati, Ohio

Dorothy E. Vatner
The University of Medicine & Dentistry of New Jersey
New Jersey Medical School
Newark, New Jersey

Stephen F. Vatner
The University of Medicine & Dentistry of New Jersey
New Jersey Medical School
Newark, New Jersey

Sonia Verp
School of Life Sciences and “Frontiers in Genetics” National Program
Ecole Polytechnique Fédérale de Lausanne (EPFL)
Lausanne, Switzerland

Jie Wang
Department of Molecular and Cellular Biology
Baylor College of Medicine
Houston, Texas

Xavier Warot
Institut Clinique de la Souris (ICS)
Illkirch, France and
Ecole Polytechnique Fédérale de Lausanne
Lausanne, Switzerland

David H. Wasserman
Department of Molecular Physiology and Biophysics
Vanderbilt University School of Medicine
Nashville, Tennessee,
Mouse Metabolic Phenotyping Center
Vanderbilt University School of Medicine
Nashville, Tennessee, and
Diabetes Research Training Center
Vanderbilt University School of Medicine
Nashville, Tennessee

Linda L. Waterman
The Jackson Laboratory
Bar Harbor, Maine

Benedikt Wefers
Helmholtz Center Munich
Institute for Developmental Genetics
Munich, Germany

Olivia Wendling
Institut Clinique de la Souris (ICS)
Illkirch, France and
Institut de Génétique et de Biologie Moléculaire et Cellulaire
CNRS/INSERM/Université Louis Pasteur
Illkirch, France

Esther Wilk
Department of Infection Genetics
Helmholtz Centre for Infection Research and University of Veterinary Medicine Hannover
Braunschweig, Germany

Graham R. Williams
Molecular Endocrinology Group
Department of Medicine
Imperial College London
Hammersmith Campus
London, United Kingdom

Phillip E. Williams
Department of Surgery
Vanderbilt University School of Medicine
Nashville, Tennessee and
Diabetes Research Training Center
Vanderbilt University School of Medicine
Nashville, Tennessee

J. Witton
Pfizer Applied Neurophysiology Group
School of Physiology and Pharmacology
University of Bristol
Bristol, United Kingdom

John N. Wood
Molecular Nociception Group
Wolfson Institute for Biomedical Research
University College London
London, United Kingdom and
London Pain Consortium
Kings College London
London, United Kingdom

Christine I. Wooddell
Roche Madison Inc.
Madison, Wisconsin

Wolfgang Wurst
Helmholtz Center Munich
Institute for Developmental Genetics
Munich, Germany,
Chair for Developmental Genetics
Technische Universität München
Munich, Germany
Chair for Developmental Genetics
Technische Universität München
Munich, Germany,
Max Planck Institute of Psychiatry
Molecular Neurogenetics
Munich, Germany, and
Deutsches Zentrum für Neurodegenerative Erkrankungen
Standort München
Munich, Germany

Shunbin Xiong
Department of Genetics
University of Texas MD Anderson Cancer Center
Houston, Texas

Deng Ping Yin
Department of Surgery
Vanderbilt University School of Medicine
Nashville, Tennessee and
Mouse Metabolic Phenotyping Center
Vanderbilt University School of Medicine
Nashville, Tennessee

Guofeng Zhang
School of Anatomy and Human Biology
The University of Western Australia
Crawley, Australia

Ruina Zhang
Department of Molecular and Cellular Biology
Baylor College of Medicine
Houston, Texas

Xiaomei Zhang
Lester and Sue Smith Breast Center
Baylor College of Medicine
Houston, Texas

Xin Zhao
The University of Medicine & Dentistry of New Jersey
New Jersey Medical School
Newark, New Jersey