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Current Protocols in Pharmacology

Current Protocols in Pharmacology

Last Update: January 10, 2018
Print ISSN: 1934-8282
Online ISSN: 1934-8290


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What's New in Current Protocols in Pharmacology
Supplement 79, December 2017

Unit 3.14 In Vitro Histone Acetylation Assay
         Abstract | Full Text:  HTML   PDF

Unit 9.25 Overview of microRNA Modulation in Analgesic Research
         Abstract | Full Text:  HTML   PDF

Unit 9.26 In Vitro Validation of miRNA-Mediated Gene Expression Linked to Drug Metabolism
         Abstract | Full Text:  HTML   PDF

Unit 12.16 Overview of Monoamine Transporters
         Abstract | Full Text:  HTML   PDF

Unit 12.17 In Vitro Assays for the Functional Characterization of the Dopamine Transporter (DAT)
         Abstract | Full Text:  HTML   PDF

Developed by pharmacologists and medicinal chemists from academia and industry, Current Protocols in Pharmacology is a key reference work that documents the broad spectrum of integrative techniques used in drug discovery and in the study of disease pathophysiology. The individual units present basic pharmacological techniques, from an assessment of the efficacy of new compounds to the safety pharmacology studies necessary for the regulatory filing of an Investigational New Drug (IND) application. Accompanying expert overviews provide perspective and context, making it easy for newcomers and professionals alike to profitably use Current Protocols in Pharmacology to its fullest extent.

A subscription gives you access to all the content in the collection plus four quarterly issues of new and updated content. Current Protocols in Pharmacology...

  • covers the full range of molecular, cellular, and in vivo pharmacological techniques used in the discovery and study of drugs and NCEs in the anti-infective, cardiovascular, inflammatory (including respiratory and arthritis), neurological, oncological, pain, and psychiatric therapeutic areas
  • presents state-of-the-art techniques for characterizing the interaction of known drugs and NCEs with receptors and enzymes at the molecular and functional levels, together with proven preclinical models of the human disease state to assess efficacy, selectivity, and side effect liabilities
  • provides timely and authoritative overviews on receptor theory and the drug discovery process, from target identification and compound screening to the preclinical IND process

Edited by: S.J. Enna, Editor-in-Chief (University of Kansas Medical Center); Michael Williams, Editor-in-Chief (Northwestern University Feinberg School of Medicine); Terry Kenakin (University of North Carolina School of Medicine); Paul McGonigle (Drexel University College of Medicine); Bruce Ruggeri (Incyte Corporation); Alan D. Wickenden (Janssen Research & Development, LLC); Guest Editor: Ines de Lannoy (InterVivo Solutions); Past Editors: John F. Barrett, James Ellis, John W. Ferkany, Roger Frechette, Paul Moser, Roger D. Porsolt, and James P. Sullivan; Past Guest Editors: Brendan J. Canning and Xi-Ping Huang (University of North Carolina)

Developmental Editor: Gwen P. Taylor

While the authors, editors, and publisher believe that the specification and usage of reagents, equipment, and devices, as set forth in this book, are in accord with current recommendations and practice at the time of publication, they accept no legal responsibility for any errors or omissions, and make no warranty, express or implied, with respect to material contained herein. In view of ongoing research, equipment modifications, changes in governmental regulations, and the constant flow of information relating to the use of experimental reagents, equipment, and devices, the reader is urged to review and evaluate the information provided in the package insert or instructions for each chemical, piece of equipment, reagent, or device for, among other things, any changes in the instructions or indication of usage and for added warnings and precautions. This is particularly important in regard to new or infrequently employed chemicals or experimental reagents. Moreover, the information presented herein is not a substitute for professional judgment, especially as concerns any applications in a clinical setting or the interpretation of results thereby obtained.