Cytokine, Growth Factor, and Chemokine Ligand Database

Cytokines, chemokines, and growth factors are soluble proteins produced by leukocytes and other cell types, which act as chemical communicators between cells and tissues within the body. These proteins mediate a number of functions, ranging from effects on cell growth, differentiation, survival, and a number of effector activities. The main purpose of this unit is to provide an easy-to-use reference summarizing some of the current information on well-established cytokine, growth factore, and chemokine ligands. The information provided is confined largely to alternative names, protein properties, genetic chracteristics, chromosomal localization, cellular expression patters, cellular-tissue targets, stimuli regulating expression, functional properties, expression analysis, and clinical utility.