Spinal Inflammation
J. Randy Jinkins1, David D. Stark1
1Downstate Medical Center, State University of New York, Brooklyn, New York
1Downstate Medical Center, State University of New York, Brooklyn, New York
Publication Name:
Current Protocols in Magnetic Resonance Imaging
Unit Number:
Unit A8.4
DOI:
10.1002/0471142719.mia0804s01
Online Posting Date:
August, 2001 Abstract
This unit presents a basic protocol for conventional and fast spin echo imaging of spine for evaluation of infections involving the CNS. The epidemic of acquired immunodeficiency syndrome (AIDS) and the frequency of CNS infections has been on the rise. An alternate protocol is presented for coronal acquisition that may be helpful to analyze the perispinal tissues for abscess formation.
Materials
Basic Protocol: Conventional and Fast Spin Echo
Materials
- Normal saline (0.9% NaCl), sterile
- Gadolinium-based MR contrast agent (e.g., Magnevist, Omniscan, or Prohance)
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Figures
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Figure A8.4.1Thoracic spondylodiscitis (Staphylococcus aureus). (A) Sagittal T
1 -weighted (TR = 500 msec, TE = 10 msec) image shows poor definition of the intervertebral disc at T5-T6 and an anterior and epidural spinal mass. Also the vertebral body marrow of T5 and T6 is hypointense. (B) Sagittal T2 -weighted (TR = 4000 msec, TE = 100 msec) MR shows abnormal hyperintensity in the marrow of T5 and T6 with early segmental collapse of the spinal column. Anterior epidural and prevertebral mass for motion (arrows) is also noted. (C) Intravenous gadolinium enhanced T1 -weighted (TR = 500 msec, TE = 10 msec) image shows abnormal enhancement of the T5 and T6 vertebral body marrow, as well as the enhancing prespinal and anterior epidural inflammatory spinal mass (arrows).
Literature Cited
| Literature Cited | |
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| Jinkins, J.R., Gupta, R., Chang, K.H., and Rodriguez-Carbajal, J. 1995. MR imaging of central nervous system tuberculosis. Radiol. Clin. North Am. 33:771-786. | |
| Modic, M.T., Feiglin, D.H., Piraino, D.W., et al. 1985. Vertebral osteomyelitis: Assessment using MR. Radiology 157:157-166. | |
| Post, M.J.D., Sheldon, J.J., Hensley, G.T., et al. 1986. Central nervous system disease in acquired immunodeficiency syndrome: Prospective correlation using CT, MR imaging, and pathologic studies. Radiology 158:141-148. | |
| Post, M.J.D., Sze, G., Quencer, R.M., et al. 1990. Gadolinium enhanced MR in spinal infection. J. Comput. Assist. Tomogr. 15:721-729. | |
| Provenzale, J.M. and Jinkins, J.R. 1997. Brain and spine imaging findings in AIDS patients. Radiol. Clin. North Am. 35:1127-1166. | |
| Reddy, S., Leite, C.C., and Jinkins, J.R. 1995. Imaging of infectious disease of the spine. In Spine: State of the Art Reviews,Vol. 9 (R.R. Lee, ed.) pp. 119-140. Hanley & Belfus, Philadelphia. | |
| Sharif, H.S., Clark, D.C., Aabed, M.Y., et al. 1990. Granulomatous spinal infections: MR imaging. Radiology 177:101-107. | |
| Shellock, F.G. 1996. Pocket Guide to MR Procedures and Metallic Objects. Lippincott-Raven, Philadelphia. | |
| Sklar, E.M., Post, M.J.D., and Lebwohl, N.H. 1993. Imaging of infection of the lumbosacral spine. Neuroimag. Clin. North Am. 3:577-590. | |
| Thurnher, M.M., Jinkins, J.R., and Post, M.J.D. 1997. Diagnostic imaging of infections and neoplasms affecting the spine in patients with AIDS. Neuroimag. Clin. North Am. 7:341-357. | |
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