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MRI of the Adrenal Glands

Kathy Wilber1,  Richard Semelka1,  Laurie Fisher2

1University of North Carolina, Chapel Hill, North Carolina
2Siemens Uptime Service Center, Cary, North Carolina


Unit Number: 
Unit A17.1
DOI: 
10.1002/0471142719.mia1701s00
Online Posting Date: 
May, 2001
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Abstract

MRI is an effective method to evaluate adrenal pathology. This unit presents a protocol incorporating various types of T1- and T2-weighted sequences, including the use of in-phase and out-of-phase gradient echo techniques and the routine use of intravenous gadolinium.

     
 
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Table of Contents

  • Unit Introduction
  • Basic Protocol: Adrenal Imaging
  • Commentary
  • Bibliography
  • Figures
  • Tables
     
 
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Materials

Basic Protocol: Adrenal Imaging

 Materials
  • Normal saline (0.9% NaCl), sterile, 40 ml minimum
  • Extravascular contrast agent (e.g., Magnevist, Omniscan, or Prohance), volume is prescribed by patient weight
     
 
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Figures

  • Figure A17.1.1
    Unenhanced fat suppressed transverse spoiled gradient echo image.

  • Figure A17.1.2
    Out-of-phase transverse spoiled gradient echo image.

  • Figure A17.1.3
    Immediate post contrast transverse spoiled gradient echo image.

  • Figure A17.1.4
    One-minute post gadolinium spoiled gradient echo transverse image.

  • Figure A17.1.5
    Post-contrast fat suppressed transverse spoiled gradient echo image.

Literature Cited

 Literature Cited
    Bilbey, J.H., McLoughlin, R.F., Kurkjian, P.S., Wilkins, G.E.L., Chan, N.H.L., Schmidt, N., and Singer, J. 1995. MR imaging of adrenal masses: Value of chemical-shift imaging for distinguishing adenoma from other tumors. Am. J. Roentgenol. 164:637-642.
    Korobkin, M., Lombardi, T.J., Aisen, A.M., Francis, I.R., Quint, L.E., and Dunnick, N.R. 1995. Characterization of adrenal masses with chemical shift and gadolinium-enhanced MR imaging. Radiology 197:411-418.
    Korobkin, M., Giordano, T.J., Brodeur, F.J., Francis, I.R., Siegelman, E.S., Quint, L.E., Dunnick, N.R., Heiken, J.P., and Wang, H.H. 1996. Adrenal adenomas: Relationship between histologic lipid and CT and MR findings. Radiology 200:743-747.
    Lee, M.J., Mayo-Smith, W.M., Hahn, P.F., Goldberg, M.A., Boland, G.W., Saini, S., and Papanicolaou, N. 1994. State-of-the-art MR imaging of the adrenal gland. RadioGraphics 14:1015-1029.
    Mayo-Smith, W.W., Lee, M.J., McNicholas, M.M.J., Hahn, P.F., Boland, G.W., and Saini, S. 1995. Characterization of adrenal masses (<5 cm) by use of chemical shift MR imaging: Observer performance versus quantitative measures. Am. J. Roentgenol. 165:91-95.
    McNicholas, M.M.J., Lee, M.J., Mayo-Smith, W.W., Hahn, P.F., Boland, G.W., and Mueller, P. 1995. An imaging algorithm for the differential diagnosis of adrenal adenomas and metastases. Am. J. Roentgenol. 165:1453-1459.
    Mitchell, D.G., Grovello, M., Matteucci, T., Peterson, R.O., and Miettinen, M.M. 1992. Benign adenocortical masses: Diagnosis with chemical shift MR imaging. Radiology 185:345-351.
    Outwater, E.K., Siegelman, E.S., Radecki, P.D., Piccoli, C.W., and Mitchell, D.G. 1995. Distinction between benign and malignant adrenal masses: Value of T1-weighted chemical-shift MR imaging. Am. J. Roentgenol. 165:579-583.
    Outwater, E.K., Siegelman, E.S., Huang, A.B., and Birnbaum, B.A. 1996. Adrenal masses: Correlation between CT attenuation value and chemical shift ratio at MR imaging with in-phase and opposed-phase sequences. Radiology 200:749-752.
    Reinig, J.W., Stutley, J.E., Leonhardt, C.M., Spicer, K.M., Margolis, M., and Caldwell, C.B. 1994. Differentiation of adrenal masses with MR imaging: Comparison of techniques. Radiology 192:41-46.
    Shellock, F.G. and Kanal, E. 1996. Magnetic Resonance: Bioeffects, Safety, and Patient Management. Lippincott, Williams & Wilkins, Philadelphia.
    Tsushima, Y., Ishizaka, H., and Matsumoto, M. 1993. Adrenal masses: Differentiation with chemical shift, fast low-angle shot MR imaging. Radiology 186:705-709.
 Key References
    Shellock and Kanal, 1996. See above.

Covers a number of important patient management issues related to MR imaging, including recommended safety procedures, a list of metallic implants that have been tested for MR compatibility, and a list of other sources on MR safety.

     
 
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